While this study tries to explain the development and evolution of placebo drugs from past to present, the benefits of these drugs to society, the individual, medicine and psychology will be explained, and comments and discussions on the use of these drugs will be put forward. It is aimed that the related study will contribute to the knowledge and interest of the researcher on the subject and help scientists who want to reach a comprehensive introduction and introductory research on placebo drugs. Although there are studies in the literature in this context, it is noteworthy that there is no study that addresses the increasing psychological and physiological problems in the post-COVID-19 period. The relevant study will share the developments and achievements of the last century in general terms, and will also include a COVID-19 section that is expected to contribute to the literature.
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