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Background: Urocortin 1 (UCN1) has cardiostimulatory, vasodilatory, diuretic and natriuretic effects, and its expression increases in heart failure (HF).

Aims: We assessed the outcome of hospitalized coronavirus disease 2019 (COVID-19) patients with heart failure (HF) compared with patients with other cardiovascular disease and/or risk factors (arterial hypertension, diabetes, or dyslipidaemia). We further wanted to determine the incidence of HF events and its consequences in these patient populations.

The RAMSES study showed a higher prevalence of OAC use among NVAF patients than that reported in previous studies. Although NOACs were preferred over VKAs in daily cardiology practice, there is a need for improved OAC therapies for NVAF patients.

A total of 1098 patients (male, 47.5%; mean age, 83.5±3.1 years) aged ≥80 years and 4596 patients (male, 50.2 %; mean age, 71.1±4.31 years) aged 65-79 years were enrolled in this study . The prevalence of HF was 39.8% for patients who were ≥80 years and 27.1% for patients 65–79 years old. For patients aged ≥80 years with HF, the prevalence rate was 67% for hypertension (HT), 25.6% for diabetes mellitus (DM), 54.3% for coronary artery disease (CAD), and 42.3% for atrial fibrillation. Female proportion was lower in the HFrEF group (p=0.019). The prevalence of HT and DM was higher in the HFpEF group (p<0.01), whereas CAD had a higher prevalence in the HFrEF group (p=0.02). Among patients aged 65–79 years, 43.9% (548) had HFpEF, and 56.1% (700) had HFrEF. In this group of patients aged 65-79 years with HFrEF, the prevalence of DM was significantly higher than in patients aged ≥80 years with HFrEF (p<0.01). Conclusion: HF is common in elderly Turkish population, and its frequency increase

Summary Background: QT dispersion has been shown to be associated with fatal arrhythmias and sudden death in coronary artery disease. A recent study indicated that marked QT dispersion in electrocardiograms (ECGs) obtained during acute ischemia demonstrated a significant correlation with ventricular tibrillation. Hypothesis: This study investigated the ECG parameters for repolarization (QT dispersion, corrected QT, corrected QT dispersion, and QT dispersion ratio) and their interrelation with acute ischemia. Merh0d.s: QT parameters as well as a newly developed repolarization index, QT dispersion ratio [(QT dispersion/RR interva1)X 1001 were calculated digitally during rest and ischemia in 32 patients with coronary artery disease (rest angina, Braunwald class III) . Results were correlated with clinical consequences, mainly arrhythmias, within a follow-up period of 5 k 2 days. RPSM~LSS: While most patients had an increase in all four parameters, only the QT dispersion ratio s

Mitral stenosis (MS) is generally the sequel of rheumatic carditis occurring in childhood (1). MS is particularly observed in developing countries (1, 2). Untreated patients can develop irreversible right ventricular failure (1, 2). Since its introduction by Inoue, percutaneous mitral balloon valvuloplasty (PMBV) is considered the leading and effective treatment option for symptomatic moderate to severe MS with favorable valve morphology (3, 4). PMBV provides immediate and sustained hemodynamic improvement, comparable with the results of surgery (3). However, there are challenges in some cases of PMBV, where surgery is also not feasible. Various techniques have been described for directing the mitral balloon catheter to left ventricle during PMBV (5-9). Here we aim to define a new technique for challenging cases of PMBV in patients with a large left atrium and a severe MS called the venoarterial looping.

Peripheral Artery Disease and Atrial Fibrillation: The Dangerous Combination Ahmet Keser, Kerem Özbek, Hüseyin Katlandur, Şeref Ulucan PMID: 27386782 DOI: 10.1016/j.jacc.2016.03.594 Free article

All HHR indices were found to be significantly decreased in patients with erectile dysfunction (p<0.001). Effort capacity was markedly lower (9.1±2.3 vs. 10.4±2.3 METs, p=0.002) among patients with erectile dysfunction. HRR1 and HRR3 were found to be an independent risk factor for erectile dysfunction (Beta=0.462, p<0.001; Beta=0.403, p<0.001; respectively) in linear regression analysis.

Objectives: The aim was to study transradial approach (TRA) and transfemoral approach (TFA) in terms of feasibility, effectiveness, usefulness, and procedure characteristics in patients having ST-segment elevation myocardial infarction (STEMI) and undergoing primary percutaneous coronary intervention (PCI) ). Along with the said aim, major adverse cardiovascular events (MACE) at follow-ups were also compared. Methods: The present study was conducted on 344 consecutive patients having ST-segment elevation myocardial infarction and qualifying for PCI. Patients were classified into two groups according to radial and femoral approaches. Patients were followed-up for MACE. Results: PCI was found to be successful in all patients. In TRA group the time between the end of the intervention to removal of the sheath, and duration of mobilization and hospitalization were significantly shorter when compared to TFA group (12 ± 2 minutes vs. 240 ± 12 minutes; P = 0.001, 13 ± 2 hours vs. 22 ± 2 hours;