Effect of Transarterial Radioembolization Therapy on Survival in Intrahepatic Cholangiocellular Carcinomas
Objective: The aim of this study is to present the survival results of patients with intrahepatic cholangiocellular carcinoma who were treated with transarterial radioembolization and who were not amenable to surgical treatment.
Materials and Methods: 28 patients who were diagnosed with intrahepatic cholangiocellular carcinoma and were not suitable for surgical treatment were included in this study. All patients were treated with transarterial radioembolization method. The survival times of the patients whose follow-up started after the diagnosis was made were recorded. Kaplan-Meier survival analysis was used to calculate survival times.
Results: A total of 28 patients were evaluated in the study. The average age is 60.46 years, with a minimum age of 36 years and a maximum age of 84 years. The median follow-up period of the patients was calculated as 14 months (min:3– max:33). The median survival time of the patients is 22 (min: 3 months, max: 33 months) months. In addition, the survival times of patients who received and did not receive chemotherapy, patients with solitary tumors and patients with multifocal tumors, patients with unilobar tumors and patients with bilobar tumors were calculated and no significant difference was found between the groups.
Conclusion: Although modern chemotherapy applications have increased this survival rate, they could not increase the median survival above 12 months. Considering these data, it seems that transarterial radioembolization therapy prolongs the survival time.
Year 2019, Volume 44, Issue 4, 1379 – 1385, 29.12.2019
Hüseyin Tuğsan BALLI İsa Burak GÜNEY Ferhat Can PİŞKİN Kairgeldy AİKİMBAEV
https://doi.org/10.17826/cumj.598480
