Lactoferrin is a multifunctional iron ions-binding glycoprotein that plays an active role in the defense of the human immune system against bacteria, viruses and fungi and in the regulation of the immune system. In humans, under normal conditions, lactoferrin is found in blood, mucosal secretions, gastrointestinal fluids, urine, and mostly in milk or colostrum (ie, in the first colostrum after birth) and is predominantly used in the defense system.
Because of its many benefits, researchers have begun to consider lactoferrin as a therapeutic protein. Although many of the proteins used for therapeutic purposes are used by injection (such as activated protein-c), lactoferrin becomes active by taking it orally, that is, it can be used orally. Lactoferrin will be the subject of the Journal of Biochemistry and Cell Biology to be published next June.
Prof. from the University of Calgari. Dr. Hans Vogel “We know that lactoferrin is a protein that has an important function in our innate immune system and plays an important role in our protection from bacterial, fungal, viral or protosal infections. In addition, lactoferrin can protect us from some types of cancer,” he said. In addition, Doctor Vogel says, “Some people see lactoferrin as the “Swiss army knife” of the human immune and defense system, and besides doing all this by only binding to iron, the proteins it has contribute to this process in many ways.”
The role of lactoferrin in the healing of skin injuries, the role of lactoferrin in the growth and development of the intestinal system at an early age, the role of bovine lactoferrin in the prevention of influenza, and the prevention of inflammation in premature babies, the prevention of osteoporosis, and thousands of scientific articles showing its positive benefits in bone development in children. It can be accessed from.
Another important contribution is the study, which has already been published online, by a group of Chinese researchers led by Professor Ning Li from Beijing. In this study, it was revealed that the consumption of lactoferrin-enriched milk improves the structure of the gastrointestinal flora and this improves living conditions.
On the other hand, many data have shown that lactoferrin inhibits the release of inflammatory mediators released from many active cells, and moreover, the prophylactic effect of lactoferrin suppresses cytokine production. With this feature, it has healing effects including metabolic peturbation and infection and metabolic diseases arising from endocrine functions.
The iron binding property of lactoferrin is directly related to the inhibition of microbial growth as well as modulation of motility, aggregation of pathogenic bacteria and formation of biofilm. It creates an environment where it cannot accommodate. It does not cause iron deficiency in the body. Regardless of its binding capacity of iron ions, lactoferrin interacts with microbial, viral and cell surfaces, thus preventing microbial and viral contamination and preventing entry into host cells.
Lactoferrin is not only a defense factor against mucosal infections, but also interacts with the viral infection process as a multi-purpose regulator. The anti-viral activity of lactoferrin has been demonstrated in both naked and closed cells, seen in the initial stage of infection, which effectively prevents infection or virus from reaching the host cell. This activity is mediated by binding to heparan sulfate glycosaminoglycan cell receptors or by viral particle or both. The anti-viral effect of lactoferrin seems to prevent us from taking unnecessary antibiotics due to viral infections in winter…. The nuclear localization of lactoferrin in different human epithelial cells makes the antiviral effect of lactoferrin not only by virus-cell superficial interaction in the early phase, but also by cell-cell surface interaction. interacts between them.
The capacity of lactoferrin to exert potentially anti-viral activity through binding to host cells and or viral viral particles, its nuclear localization makes lactoferrin an important brick in the mucosal wall, effective against viral attacks and as a new strategy in the treatment of viral infections. strengthens the idea that it can be implemented.
Lactoferrin as mentioned above; It is a multifunctional protein and the most essential element of the natural immune system. On the other hand, according to the data of the World Health Organization, cancer includes 13% of the total deaths in the world.
The five most important forms of cancer are lung, colorectal, stomach, liver and breast cancer. Lactoferrin is a glycoprotein that binds iron ions with its antibacterial, antioxidant and anticarcinogenic effects.
It is produced in the exocrine glands and is also released by many external fluids as a first-stage defense. Lactoferrin also has the feature of inducing apoptosis and suppressing the spread of cancer, and the capacity to reconstruct the white and red blood cell balance that is deteriorated after chemotherapy. It makes people resilient. It also showed significant improvements in quality of life scores in cancer patients.
Of course, lactoferrin is not a drug, but it is a quality life tool that should be used regularly and recommended not only by patients but also by healthy people in order not to get sick and for a healthy life.
Today, people who do not have money to spend to look young and beautiful will now have the same healthy and quality life with one tablet of lactoferrin a day….
Biochemistry and Cell Biology, 2012, 90(3) , journal June has completely allocated the number of bears to lactoferrine tablets
Those who are interested can read the abstracts by using the link below
or
or access detailed medical articles and studies from www.pubmed.com
, especially those with cancer around them should be more careful.
thanks for your interest
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