41 studies were included in a meta-analysis, and the ODDS ratio was calculated by using the ODDS ratio for which features increase the cancer risk in thyroid ultrasonography.
In thyroid ultrasonography, if the height of the nodule is greater than its width, the risk of cancer increases 10.15 times.
The disappearance of the halon in the thyroid nodule increases the cancer risk 7.14 times, and the irregular border increases 6.12.
Microcalcification in the thyroid nodule increases the risk of cancer 6.76 times
. 
Hypoechoic thyroid nodule increases the risk of cancer 5.07 times
. 
Intranodular vascularization in the thyroid nodule increases the risk of cancer 3.76 times
. 
Thyroid nodule >4 cm increases the risk of cancer 1.63 times
Source: Campanella P, Ianni F, Rota CA, Corsello SM, Pontecorvi A. Quantification of cancer risk of each clinical and ultrasonographic suspicious feature of thyroid nodules: a systematic review and meta-analysis. Eur J Endocrinol. 2014 Apr 10;170(5):R203-11. doi: 10.1530/EJE-13-0995
Assistant Prof. Dr. Fevzi Balkan
