Systemic lupus erythematosus (abbreviated as lupus); It is a chronic inflammatory disease in which the immune system fights by targeting its own tissues and organs. Lupus can affect many organs and systems, including the skin, kidneys, blood cells, brain, heart, and lungs. Lupus can be difficult to diagnose, as there may be signs of involvement of many organs and systems. Since it causes many complaints and findings in a wide spectrum and can mimic many diseases; lupus is also called the “great copycat” by doctors. The most distinctive finding of lupus is a butterfly-shaped skin rash (malar rash) on the face that extends from the nose to the cheeks; although this is most common, it may not be present in all lupus patients. Most patients have malaise, skin rash, arthritis and fever. In summary, the general features of lupus:
– The disease progresses with exacerbations ranging from mild to severe.
– Women are affected 9-10 times more often than men.
– Treatment depends on the location and severity of the involvement
– Lupus shows different features of involvement in each person
– Lupus cannot be completely eliminated with treatment. However, it is possible to control the disease and prevent tissue and organ damage with drug therapy.
What are the causes of lupus?
The immune system (immune system) is the defense system of our body. By producing certain proteins (such as immunoglobulin) or through its cells, it protects us from foreign microbes and cancer. In lupus, the immune system goes astray, and the body fights against its own cellular structures, resulting in inflammation and related damage to many organs and systems. It is unknown what causes this. However, in lupus, as in all autoimmune systemic connective tissue diseases, an abnormal immune response occurs as a result of the interaction of the individual’s appropriate genetic makeup and environmental factors (infections, sunlight, drugs, toxins, etc.).
Who does lupus get?
Lupus usually begins in the 20s and 30s, although it can occur at any age. It is 10 times more common in women than men. Although the disease is seen in all races, it is more common and more serious in blacks, Hispanics and Asians.
