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Mucin deficiency in dry eye

by clinic

The tear layer consists of mucin, which keeps the eye moist at the bottom, water in between, and oil on the top. This is called a tear film. The mucus formed by mucin forms the base of the tear film.

It moisturizes the eye tissues, protects the upper surface by plastering the surface and softens them. When mucin loses its water, liquid mucus that provides lubrication is formed.

Mucus prevents the tissue from being damaged chemically or physically.
*Mucin is secreted from goblet cells in the conjunctiva. * Adjusts the surface tension between the epithelium and the tear film layer.
* When mucin loses its water, a slippery liquid called mucus appears. It relaxes the eyes due to the slipperiness of the mucus. Mucin insufficiency can be examined in two separate groups as “killing the goblet” and “situations that can spoil the mucin”.

Goblet killing: What kills goblet cells? The life span of goblet cells is 3-4 days. You should consider the event as the production of new cells.
The conjunctiva is the thin membrane that covers the white layer of the eye, the sclera. The goblet cells in this membrane are from any condition that causes disruption of the conjunctiva.
is affected.

* Insomnia, sleeping late. *Dusty environments *Pollens*Cigarette smoke *Excessive sun and light. * Ptergium * Toxic substances * Inflammatory conditions: Inflammation of the eyelash root called blepharitis is one of the most important reasons.

Conditions that spoil the mucin: *If benzalkonium chloride, the preservative in dry eye drops, is dropped too much, it will have the opposite effect and kill the goblet.

* The decrease in the oil of the tears disrupts the tear layer and therefore the mucus order.

*Conditions that impair the balance, quality and density of tears, eyelash root inflammation, infections…. adversely affect mucin.

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